Research at Westmead

The Cancer Research Unit conducts trailblazing work on telomeres, which are important for senescence (aging) and all cancers.

The Cell Biology Unit focuses on one of the major factors in at least 85% of all cancers affecting children and adults: the molecule telomerase.

The Cell Signalling Unit is developing new treatments for a range of diseases, such as epilepsy, cancer, kidney disease, and infectious diseases like coronaviruses.

The Computational Systems Biology Unit develops computational methods and uses systems approaches to characterise cell identity and cell-fate decisions during stem cell differentiation and development.

The Embryology Unit studies how development occurs in order to understand what goes wrong in birth defects.

The Eye Genetics Research Unit aims to understand the genetic causes of eye diseases to improve diagnosis and treatment.

The Gene Therapy Research Unit finds ways to correct genetic diseases in children.

The Genome Integrity Unit investigates how cells maintain their DNA health with specific interests in cancer and early development.

Focuses on two complementary fields: stem cell research and regenerative medicine.

Focuses on answering fundamental questions, such as how does the brain work? And at the same time asking how a disease state can upset brain function. This fundamental knowledge is then applied to identify new potential drug targets.

We focus on understanding the molecular mechanisms underlying telomere length regulation and how telomere length can be manipulated to control cell division.

We like to think of ourselves as “translational tool makers” as we develop and improve vector-based tools that can be used in wide range of basic and preclinical studies, as well as in clinical applications.

The Nuclear Dynamics Group investigates how cells attempt to re-organise cellular architecture to resolve threats on genome stability. We use highly specialised techniques, including super-resolution microscopy and live cell imaging, to track changes in the structure and movement of molecules within the nuclei of cells.

The Molecular Neurobiology Lab at Kids Research, Westmead Children’s Hospital has been stuying the pathogenic mechanisms of Rett syndrome for the past 9 years and conducts a program of interdisciplinary research spanning fields of neurology, neuropathology, fundamental neuroscience, clinical chemistry and pharmacology

This lab is researching how we could improve diagnosis, prognosis and treatment decisions in the future with different types of molecular data from a child’s cancer.

The ACRF International Centre for the Proteome of Human Cancer ProCan scientists at CMRI are analysing tens of thousands of examples of all types of cancer from all over the world to develop a library of information to advance scientific discovery and enhance clinical treatment worldwide.

Read more details about CMRI’s Research Teams